Toufigh Gordi, PhDback to Management Team>
President, PK/PD and Clinical Pharmacology Services
Dr. Gordi is the President of Rosa’s PK/PD and Clinical Pharmacology Services. He is an accomplished clinical pharmacologist and pharmacometrician with significant industry, academic, and consulting experience. Dr. Gordi has conducted dozens of PK/PD modeling and trial design engagements in a wide range of disease areas, managed numerous clinical trials, advised business development and marketing groups, and published over 20 papers in the areas of PK/PD modeling and clinical pharmacology in peer-reviewed journals.
Dr. Gordi’s experience spans both small and large molecules, existing and novel formulations, all phases of drug development (both preclinical and clinical), and a broad spectrum of acute and chronic disorders, including pain, postmenopausal syndrome, COPD, malaria, cardiovascular and metabolic disease, and central nervous system disorders. Prior to joining Rosa, Dr. Gordi applied his expertise in PK/PD modeling and clinical pharmacology as a consultant with large and small biopharmaceutical companies. Before that, he was employed as a Senior Pharmacometrician at Hoffman La Roche, and as Associate Director of pharmacokinetics at Depomed Inc. and at CV Therapeutics. In those companies, he created PK/PD models of preclinical and clinical data and prepared clinical pharmacology and phase 2 study protocols, including first in human and special population studies. He also performed PK/PD analyses of phase 3 study data, prepared biopharmaceutical and clinical pharmacology sections of NDAs, created PK/PD models used in NDAs and supplementary NDAs, and contributed significantly to IND and end of phase 2 documentation for the FDA. In addition, he was a Clinical Pharmacology Program Leader at Pharmacia Singapore, Pte. Ltd, where he designed and conducted ethnic bridging studies.
Dr. Gordi holds a Ph.D. in Pharmacokinetics and Pharmacodynamics from Uppsala University, Uppsala, Sweden, and a M.Sc. in Pharmacy from the same university. As a Ph.D. student, Dr. Gordi initiated, coordinated, and managed 3 clinical studies in Vietnam involving healthy subjects and patients with malaria to investigate the antimalarial agent, artemisinin. He studied the pharmacological properties of artemisinin, including its enzyme induction capabilities, its clinical efficacy in different dosing regimens, and the relationship between its concentrations in saliva, capillary plasma, and venous plasma.
His postdoctoral training was performed in the laboratory of Dr. William Jusko, in the Department of Pharmaceutical Sciences, State University of New York, Buffalo.
Dr. Gordi founded the Bay Area PK/PD Network as a means for San Francisco area PK/PD specialists to exchange ideas and remain abreast of new developments in the field.
On those rare occasions that he is not spending time with his daughter and twin sons, Dr. Gordi likes to climb the walls (indoor), bike (up the hills), and scuba dive (in the cold waters off the coast of California).