Book Chapter/Handbook

Saroja Ramanujan, Kapil Gadkar, Ananth Kadambi

Quantitative Systems Pharmacology: Applications and Adoption in Drug Development. In Systems Pharmacology and Pharmacodynamics

Abstract

Theresa Yuraszeck, Derek Bartlett, Indrajeet Singh, Mike Reed, Matthias Klinger, Sharan Pagano, Min Zhu

A quantitative systems pharmacology (QSP) model to assess the action of blinatumomab in NHL patients (pts)

Presented by Amgen and Rosa at the American Society of Clinical Oncology meeting, 2016.

Poster

CM Friedrich, CM Witt, MM Pryor, T Rooney, A Genevois-Borella, MC Obinu, A Guerreiro, J Konop, MJ Reed, Z Bocskei

Application of a quantitative systems pharmacology (QSP) model to evaluate xCT inhibition as a target for central nervous system diseases

Presented by Sanofi and Rosa at World Conference on Pharmacometrics, 2016

Poster

Christina M. Friedrich, James Soper, Colleen M. Witt, Meghan M. Pryor, Lauren Martens, Dooyoung Lee, Kelley Larson, Matthew Townsend, Cuyue Tang, Holger Patzke, Gerhard Koenig

A Quantitative Systems Pharmacology Platform of Brain and Serum Progranulin (PGRN) to Investigate Targets in Frontotemporal Dementia (FTD)

Presented by FORUM Pharmaceuticals and Rosa at American Conference on Pharmacometrics, 2016

Poster

CM Friedrich, CM Witt, MM Pryor, T Rooney, A Genevois-Borella, MC Obinu, A Guerreiro, J Konop, MJ Reed, Z Bocskei

Application of a quantitative systems pharmacology (QSP) model to evaluate xCT inhibition as a target for central nervous system diseases

Presented by Sanofi and Rosa at World Conference on Pharmacometrics (WCoP), 2016

Poster

CM Friedrich, W Zago, S Gardai, G Tonn, MJ Reed

Development of a qualitative systems pharmacology model to support hypothesis generation and testing for Parkinson's disease

Presented by Elan Pharmaceuticals, Inc and Rosa at World Parkinson Congress (WPC), 2016

Poster

CJ Musante, S Ramanujan, M Zager, V Damian, M Weis, J Woodhead

The International Society of Pharmacometrics’ (ISoP) Special Interest Group (SIG) on Quantitative Systems Pharmacology (QSP): Developing a Community and Advancing a Field

Presented by Pfizer Inc, Genentech Inc, Janssen Pharmaceutical Companies of Johnson & Johnson, GalaxoSmithKline, DILIsym Services Inc, and Rosa at the Population Approach Group in Europe Conference (PAGE), 2016

Conference Presentation

S Pagano

Mechanistic Physiological PhysioPD™ Models in Drug Development: A Proven Quantitative Systems Pharmacology (QSP) Approach.

Presented at Clinical and Pharmaceutical Solutions through Analysis (CPSA), 2016

Peer Reviewed Journal Publication

CM Friedrich

A model qualification method for mechanistic physiological QSP models to support model-informed drug development

Published in CPT Pharmacometrics Syst Pharmacol 5(2): 43-53, 2016

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