De-risking Drug Development with Mechanistic Insights

PhysioPD Research

PhysioPD Research is a proprietary approach that translates the physiology, disease pathophysiology, and drug pharmacology of interest into a customized and interactive mathematical Research Platform. PhysioPD delivers credible insights that would be impossible to obtain in any other way. It is used by scientists and clinicians to clarify the connection between disease mechanisms, therapeutic interventions, and clinical outcomes. The result is that decision-makers have a dramatic increase in confidence to develop successful clinical trials and product submissions.

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PhysioPD Research

Trusted Partners in Pharmaceutical Innovation

For over two decades, Rosa & Co. has partnered with top pharmaceutical and biotechnology companies to unlock the potential of their therapies. These are just a selection of companies that have published with us. Our work helps understand mechanisms of action, optimize dosing strategies, identify key biomarkers, and predict clinical outcomes. Discover the transformative insights our collaborations have generated. Read our case studies or contact us to learn more.

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Explore our Worldwide Webinar Series

Rosa’s "Impact" webinar series is renowned for its informative discussions on the use of computer modeling and simulation within the global research and development community. Register for an upcoming webinar or download a webinar from the archives.

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Explore our Worldwide Webinar Series

Recent Highlights

FDA and non-profit create MIDD course for drug development scientists

The U.S. Food and Drug Administration’s (FDA’s) Center for Drug Evaluation and Research (CDER) Quantitative Medicine Center of Excellence (QM CoE), in collaboration with CDER’s Office of Translational Sciences and the Critical Path Institute (C-P... Read More

Rosa presentations at ACoP15

Rosa will present four posters at the Fifteenth American Conference on Pharmacometrics (ACoP15).    Monday, November 11th"A translational QSP model to characterize the preclinical pharmacodynamics of combining a KRAS G12C inhibitor with a SHP... Read More

"Rosa is all about doing better science"

—Christina Friedrich, PhD, Chief Engineer, PhysioPD

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